TNF‑α and its receptors: how TNFR1 and TNFR2 connect inflammation, survival and repair

Two TNF forms, TNFR1 ubiquitin platforms, caspase-8 and MLKL, TNFR2 signaling and the limits of translating cellular mechanisms into clinical therapy.

October 9, 2026

Resveratrol and immune signalling: STAT3, NF-κB and the contradictions of SIRT1

STAT3, NF-κB and NAD⁺-dependent deacetylation; conflicting Th17/Treg findings, pharmacokinetics and positive and negative clinical trials.

October 9, 2026

Curcuminoids: IKK, NF-κB, TNF-α, and the limits of evidence in rheumatoid arthritis

How structural differences between curcumin, DMC, and BDMC affect redox chemistry and IKK/NF-κB signaling; what positive and negative RA trials show, and where evidence of efficacy and safety ends.

October 9, 2026

All materials

Material type

Area

Popular tags

TNF‑α and its receptors: how TNFR1 and TNFR2 connect inflammation, survival and repair

Resveratrol and immune signalling: STAT3, NF-κB and the contradictions of SIRT1

Curcuminoids: IKK, NF-κB, TNF-α, and the limits of evidence in rheumatoid arthritis

Andrographis, andrographolide, NF-κB p50, and acute respiratory infection evidence