An in-depth account of ALCAR transport, acetyl exchange, acetylcholine and chromatin, mitochondrial function, and human studies of neuropathy, cognitive impairment, and depression. Studied doses are distinguished from prescriptions and cellular mechanisms from clinical outcomes.
An in-depth account of melatonin synthesis, MT1/MT2 and mitochondrial signaling, redox chemistry, cell death, and clinical chronobiology. Human studies of sleep and glucose metabolism are distinguished from neuroprotection models; formulations, interactions, and the limits of laboratory measures are explained.
An in-depth monograph on the delivery of long-chain fatty acids into mitochondria, tissue-specific CPT1 isoforms, and regulation by malonyl-CoA. It examines catalysis, AMPK–ACC, β-oxidation, energy calculations, metabolic flexibility, and inherited defects. Clinical and sports studies of carnitine, the microbial TMAO pathway, and pharmacological approaches are considered within the limits of the evidence.