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Knowledge · Supplements

Essential phospholipids and phosphatidylcholine: liver membranes, lipid remodeling, and the limits of “repair”

DLinPC chemistry, digestion and remodeling, mitochondria, PLA2, fibrosis, VLDL and bile. How model effects differ from MANPOWER, VA and EXCEL outcomes and clinical liver repair.

October 8, 2026
Knowledge · Nutrition

Fructose metabolism: KHK, ChREBP and hepatic lipid synthesis

Intestinal fructose clearance, KHK kinetics, ATP and urate metabolism, carbon routes into DNL and ChREBP/ACC/FASN regulation. Human interventions, lipotoxicity and clinical limits in MASLD.

October 8, 2026
Knowledge · Nutrition

Omega-7 and palmitoleate: a lipokine, liver fat and insulin

SCD1, lipid pools and palmitoleate signaling between organs. Conflicting mouse models, cis/trans biomarkers, a newer null metabolic RCT and limits of supplement use.

October 8, 2026