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Knowledge · Nutrition

Fructose metabolism: KHK, ChREBP and hepatic lipid synthesis

Intestinal fructose clearance, KHK kinetics, ATP and urate metabolism, carbon routes into DNL and ChREBP/ACC/FASN regulation. Human interventions, lipotoxicity and clinical limits in MASLD.

October 8, 2026
Knowledge · General

Hyperuricemia, fructose and xanthine oxidoreductase: mechanisms and evidence

Purine degradation, KHK-C, ATP and Pi, XOR, vascular and renal hypotheses. What Feig, CARES, FAST and ALL-HEART show, and why asymptomatic urate does not establish a universal treatment regimen.

October 8, 2026
Knowledge · Nutrition

Free Sugars: Fructose, Diet, and Real Risks

How free sugars differ from total and added sugars, why whole fruits and juices are not equivalent, and what trials on fructose and sugary drinks have shown. WHO guidelines, dental caries, labeling, and safe practical changes.

September 2, 2026