How to distinguish MCAS from mastocytosis and allergy; event-related tryptase, histamine, PGD₂, leukotrienes, diagnostic criteria, treatment evidence, and safety limits.

October 9, 2026

Dietary histamine, diamine oxidase, and AOC1: from enzyme reaction to clinical decisions

How DAO and HNMT handle dietary histamine, what AOC1 variants and serum tests show, and what challenge studies and small enzyme-supplement trials can establish.

October 9, 2026

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Mast Cell Activation Syndrome: Mediators, Diagnosis, and Limits of Therapy

Dietary histamine, diamine oxidase, and AOC1: from enzyme reaction to clinical decisions