Knowledge · General
The NLRP3 Inflammasome: Assembly, IL-1β, and the Limits of the Inflammaging Model
NLRP3 assembly, priming, K⁺ efflux, IL-1β/IL-18 maturation, and clinical evidence are considered separately. Inflammaging is not one sensor, and IL-1β blockade is not direct NLRP3 inhibition.