Knowledge · Supplements
Valerian Root: Valerenic Acid, GABA Receptors, and Sleep Architecture
From root composition and β2/β3-dependent GABA_A modulation to polysomnography: what is known about valerian, deep sleep, adenosine, and 5-HT5A. Clinical reviews, the glymphatic hypothesis, extract standardization, dosing, and safety—with mechanisms distinguished from outcomes in humans.