Knowledge · Nutrition
Vitamin D, VDR and antimicrobial peptides: mechanisms and clinical limits
Local vitamin D metabolism, VDR, CAMP and DEFB4: enzymes, compartments, LL-37 maturation and the limits of clinical infection prevention.
Knowledge · Nutrition
Taurine: Why the Heart and Bile Need It, Whether It Affects GABA Receptors, and Whether It Really Helps With Cramps
Evidence-based guide to taurine: aminosulfonic acid, myocardial SERCA2a calcium modulation, taurocholic bile acids, neuroprotection, and energy drink safety facts.
Knowledge · Nutrition
Betaine (TMG): Homocysteine, Methylation, Liver Health, and Exercise Performance
Evidence-based guide to betaine (trimethylglycine / TMG): BHMT enzyme, alternative homocysteine remethylation, fatty liver mitigation, cellular osmolyte, and athletic power.
Knowledge · Nutrition
L-Arginine in the Human Body: Nitric Oxide, Endothelium, Blood Pressure, Immunity, and the Limits of Supplementation
Evidence-based guide to L-arginine: eNOS substrate, nitric oxide vasodilation, wound healing collagen, first-pass arginase metabolism, herpes interactions, and safety.
Knowledge · Nutrition
L-Citrulline: Why It Raises Arginine More Effectively Than Arginine Itself, and What We Know About NO, Blood Flow, and Endurance
Evidence-based guide to L-citrulline: urea cycle, endothelial NO synthesis, bypass of first-pass hepatic arginase, citrulline malate, and vasodilation protocols.
Knowledge · Nutrition
Beta-Alanine in the Body: Carnosine, Muscle Buffering, Fatigue, and Athletic Performance
Evidence-based guide to beta-alanine: carnosine synthesis, intracellular proton buffering (H+), anaerobic exercise (1–4 min), sensory paresthesia, and loading strategies.
Knowledge · Nutrition
Vitamin D: Bones, Testing, Supplements, and the Risks of Megadoses
Evidence-based guide to vitamin D: cholecalciferol metabolism, calcium homeostasis, immune function, 25(OH)D blood testing, dosages, and toxicity risks.
Knowledge · Nutrition
Calcium in the Body: Why It Matters, How to Recognize Deficiency and Excess, and How to Choose Supplements Safely
A practical guide to calcium: its roles in bone and neuromuscular function, links with vitamin D and parathyroid hormone, food, testing and supplement safety.