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© 2026 NutriFit. All rights reserved.V1.0.2365 · 2025–2026

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Knowledge · Labs and diagnostics

Reverse T3: metabolism, tissue signaling and diagnostic limits

rT3 chemistry, DIO1/2/3, transport, receptors and mitochondria. How NTIS differs from hypothyroidism, why FT3/rT3 cannot diagnose blockade, and the limits of treatment and supplement evidence.

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October 8, 2026
Knowledge · General

Deiodinases: selenium enzymes, T4-to-T3 conversion and illness

D1/D2/D3 selenium chemistry, ring-specific reactions, compartments, transport and receptors. Reversible D2 ubiquitination, NTIS, selenium trials, Thr92Ala and the limits of laboratory conversion indices without universal treatment protocols.

October 8, 2026