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Knowledge · Labs and diagnostics

Asymmetric dimethylarginine: ADMA metabolism and vascular risk

ADMA release from methylated proteins, DDAH1 and DDAH2 catalytic evidence, AGXT2, arginine transport, and NOS inhibition. Clinical associations, measurement methods, and why a reference interval is not a treatment threshold.

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October 8, 2026
Knowledge · Labs and diagnostics

Glycemic variability and CGM: postprandial peaks and endothelium

Reading CV, TIR, and AGP; sensor chemistry, mitochondria, PARP/GAPDH, Brownlee's four branches, eNOS, and glycocalyx. Clinical findings, meal strategies, and limits of transferring targets between populations.

October 8, 2026