Iron Deficiency Calculator: TSAT, Ferritin and Ganzoni Deficit
TSAT = iron / TIBC × 100%. Ganzoni model: weight × (15 − Hb in g/dL) × 2.4 + 500 mg for weight ≥ 35 kg. It is displayed only when both Hb and ferritin are below the selected thresholds.
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Calculation
This calculation is for reference only and is not medical advice, a diagnosis or a prescription. If you have a medical condition, are pregnant, take medication or have any doubts, discuss the result with a physician or a qualified nutrition professional.
Result
- Interpretation
- Pattern not classified; these thresholds do not exclude a diagnosis
- Transferrin saturation (TSAT)
- 12.5 %
- Ferritin threshold for deficiency
- 15 µg/L
- Total iron deficit (Ganzoni)
- Not calculated: this model requires both Hb and ferritin below the selected thresholds.
- TIBC used
- 72.0 µmol/L
- Serum iron
- 9.0 µmol/L
A value < 20% is used as a reference in several clinical conditions; interpretation depends on context.
WHO 2020: < 15 µg/L in adults without inflammation. This is not a universal clinical threshold for every condition.
TSAT = iron / TIBC × 100%. Ganzoni model: weight × (15 − Hb in g/dL) × 2.4 + 500 mg for weight ≥ 35 kg. It is displayed only when both Hb and ferritin are below the selected thresholds.
These are descriptive biomarker patterns, not diagnoses. Hb thresholds: 130 g/L for men and 120 g/L for nonpregnant women; WHO 2020 ferritin: 15 µg/L, or 70 µg/L at CRP > 5 mg/L. Ganzoni target Hb, weight and stores need individual selection; the result is not a medicine dose. Reference ranges are population benchmarks from the cited sources. Laboratories use their own ranges, and interpretation depends on clinical context: discuss the result with your physician.
How it is calculated
TSAT = iron / TIBC × 100%. Ganzoni model: weight × (15 − Hb in g/dL) × 2.4 + 500 mg for weight ≥ 35 kg. It is displayed only when both Hb and ferritin are below the selected thresholds.
Formula
TSAT = iron / TIBC × 100%. Ganzoni model: weight × (15 − Hb in g/dL) × 2.4 + 500 mg for weight ≥ 35 kg. It is displayed only when both Hb and ferritin are below the selected thresholds. TIBC (µmol/L) = transferrin (g/L) × 25.1. Iron: µg/dL × 0.179 = µmol/L. Hb: g/L ÷ 10 = g/dL.
Limits of the method
These are descriptive biomarker patterns, not diagnoses. Hb thresholds: 130 g/L for men and 120 g/L for nonpregnant women; WHO 2020 ferritin: 15 µg/L, or 70 µg/L at CRP > 5 mg/L. Ganzoni target Hb, weight and stores need individual selection; the result is not a medicine dose.
Sources of the method
- WHO guideline on use of ferritin concentrations to assess iron status in individuals and populations. Geneva: World Health Organization, 2020
- Ganzoni AM. et al. [Intravenous iron-dextran: therapeutic and experimental possibilities]. Schweiz Med Wochenschr, 1970
- Venofer. Summary of Product Characteristics: Ganzoni formula and iron stores
How to use the calculation
Enter the starting values
TSAT = iron / TIBC × 100%. Ganzoni model: weight × (15 − Hb in g/dL) × 2.4 + 500 mg for weight ≥ 35 kg. It is displayed only when both Hb and ferritin are below the selected thresholds.
Adjust the parameters
TSAT = iron / TIBC × 100%. Ganzoni model: weight × (15 − Hb in g/dL) × 2.4 + 500 mg for weight ≥ 35 kg. It is displayed only when both Hb and ferritin are below the selected thresholds. TIBC (µmol/L) = transferrin (g/L) × 25.1. Iron: µg/dL × 0.179 = µmol/L. Hb: g/L ÷ 10 = g/dL.
Read the result
These are descriptive biomarker patterns, not diagnoses. Hb thresholds: 130 g/L for men and 120 g/L for nonpregnant women; WHO 2020 ferritin: 15 µg/L, or 70 µg/L at CRP > 5 mg/L. Ganzoni target Hb, weight and stores need individual selection; the result is not a medicine dose.
Frequently asked questions
What does the calculation show?
TSAT = iron / TIBC × 100%. Ganzoni model: weight × (15 − Hb in g/dL) × 2.4 + 500 mg for weight ≥ 35 kg. It is displayed only when both Hb and ferritin are below the selected thresholds.
What limitations apply?
These are descriptive biomarker patterns, not diagnoses. Hb thresholds: 130 g/L for men and 120 g/L for nonpregnant women; WHO 2020 ferritin: 15 µg/L, or 70 µg/L at CRP > 5 mg/L. Ganzoni target Hb, weight and stores need individual selection; the result is not a medicine dose.
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