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Iron Deficiency Calculator: TSAT, Ferritin and Ganzoni Deficit

TSAT = iron / TIBC × 100%. Ganzoni model: weight × (15 − Hb in g/dL) × 2.4 + 500 mg for weight ≥ 35 kg. It is displayed only when both Hb and ferritin are below the selected thresholds.

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Calculation

Sex
Serum iron — Units
What your report shows

Enter measured CRP. Zero is not a substitute for a missing test. At CRP > 5 mg/L, the ferritin reference threshold is 70 µg/L (WHO 2020).

The result updates as you change the fields. Your data never leaves the browser.

This calculation is for reference only and is not medical advice, a diagnosis or a prescription. If you have a medical condition, are pregnant, take medication or have any doubts, discuss the result with a physician or a qualified nutrition professional.

Result

Interpretation
Pattern not classified; these thresholds do not exclude a diagnosis
Transferrin saturation (TSAT)
12.5 %

A value < 20% is used as a reference in several clinical conditions; interpretation depends on context.

Ferritin threshold for deficiency
15 µg/L

WHO 2020: < 15 µg/L in adults without inflammation. This is not a universal clinical threshold for every condition.

Total iron deficit (Ganzoni)
Not calculated: this model requires both Hb and ferritin below the selected thresholds.

TSAT = iron / TIBC × 100%. Ganzoni model: weight × (15 − Hb in g/dL) × 2.4 + 500 mg for weight ≥ 35 kg. It is displayed only when both Hb and ferritin are below the selected thresholds.

TIBC used
72.0 µmol/L
Serum iron
9.0 µmol/L

These are descriptive biomarker patterns, not diagnoses. Hb thresholds: 130 g/L for men and 120 g/L for nonpregnant women; WHO 2020 ferritin: 15 µg/L, or 70 µg/L at CRP > 5 mg/L. Ganzoni target Hb, weight and stores need individual selection; the result is not a medicine dose. Reference ranges are population benchmarks from the cited sources. Laboratories use their own ranges, and interpretation depends on clinical context: discuss the result with your physician.

How it is calculated

TSAT = iron / TIBC × 100%. Ganzoni model: weight × (15 − Hb in g/dL) × 2.4 + 500 mg for weight ≥ 35 kg. It is displayed only when both Hb and ferritin are below the selected thresholds.

Formula

TSAT = iron / TIBC × 100%. Ganzoni model: weight × (15 − Hb in g/dL) × 2.4 + 500 mg for weight ≥ 35 kg. It is displayed only when both Hb and ferritin are below the selected thresholds. TIBC (µmol/L) = transferrin (g/L) × 25.1. Iron: µg/dL × 0.179 = µmol/L. Hb: g/L ÷ 10 = g/dL.

Limits of the method

These are descriptive biomarker patterns, not diagnoses. Hb thresholds: 130 g/L for men and 120 g/L for nonpregnant women; WHO 2020 ferritin: 15 µg/L, or 70 µg/L at CRP > 5 mg/L. Ganzoni target Hb, weight and stores need individual selection; the result is not a medicine dose.

Sources of the method

  • WHO guideline on use of ferritin concentrations to assess iron status in individuals and populations. Geneva: World Health Organization, 2020
  • Ganzoni AM. et al. [Intravenous iron-dextran: therapeutic and experimental possibilities]. Schweiz Med Wochenschr, 1970
  • Venofer. Summary of Product Characteristics: Ganzoni formula and iron stores

How to use the calculation

1

Enter the starting values

TSAT = iron / TIBC × 100%. Ganzoni model: weight × (15 − Hb in g/dL) × 2.4 + 500 mg for weight ≥ 35 kg. It is displayed only when both Hb and ferritin are below the selected thresholds.

2

Adjust the parameters

TSAT = iron / TIBC × 100%. Ganzoni model: weight × (15 − Hb in g/dL) × 2.4 + 500 mg for weight ≥ 35 kg. It is displayed only when both Hb and ferritin are below the selected thresholds. TIBC (µmol/L) = transferrin (g/L) × 25.1. Iron: µg/dL × 0.179 = µmol/L. Hb: g/L ÷ 10 = g/dL.

3

Read the result

These are descriptive biomarker patterns, not diagnoses. Hb thresholds: 130 g/L for men and 120 g/L for nonpregnant women; WHO 2020 ferritin: 15 µg/L, or 70 µg/L at CRP > 5 mg/L. Ganzoni target Hb, weight and stores need individual selection; the result is not a medicine dose.

Frequently asked questions

What does the calculation show?

TSAT = iron / TIBC × 100%. Ganzoni model: weight × (15 − Hb in g/dL) × 2.4 + 500 mg for weight ≥ 35 kg. It is displayed only when both Hb and ferritin are below the selected thresholds.

What limitations apply?

These are descriptive biomarker patterns, not diagnoses. Hb thresholds: 130 g/L for men and 120 g/L for nonpregnant women; WHO 2020 ferritin: 15 µg/L, or 70 µg/L at CRP > 5 mg/L. Ganzoni target Hb, weight and stores need individual selection; the result is not a medicine dose.

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Calculation assumptions

These are descriptive biomarker patterns, not diagnoses. Hb thresholds: 130 g/L for men and 120 g/L for nonpregnant women; WHO 2020 ferritin: 15 µg/L, or 70 µg/L at CRP > 5 mg/L. Ganzoni target Hb, weight and stores need individual selection; the result is not a medicine dose.

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